Aldactone
Common use
Magnium and potassium-sparing diuretic and aldosterone antagonist. It competitively associates with aldosterone receptors in in the distal parts of the nephron. It has a diuretic effect, increases excretion of natrium ions and decreases excretion of potassium and magnium, decreases urinary acidity. The diuretic effect of the medicine is moderate and appears usually after 2-5 days of treatment and continues during 2-3 days after discontinuance of the medicine intake. A weak hypotension effect appear usually in 2-3 weeks of treatment. Aldactone is used in combination with other drugs to treat hypertension. It also facilitates removal of excess fluid from the body in congestive heart failure, cirrhosis of the liver, and kidney disease.
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Dosage and direction
Daily dose for adults in arterial hypertension, edema syndrome is 50-100 mg for adults. It should be divided into 1-2 intakes a day. On necessity the dose maybe gradually increased up to 200 mg a day. Duration of treatment is not less than two weeks. For other conditions such as chronic congestive heart failure, cirrhosis, nephrotic syndrome and others different dosage maybe recommended. Consult your doctor before you decide to take this medicine. Aldactone should be taken after a meal and the most preferable is a single dose before bedtime.
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