Lozol
Common use
Lozol is a thiazide-like diuretic which contains an active substance benzamide-sulfonamide-indole (Indapamide). By its pharmacological properties it is similar to thiazide diuretics (changes of Na+ re-absorption in the vertical segment of the loop of Henle). Lozol increases excretion of Na+, Cl-, K+, and Mg2+ with urine. It is used to treat hypertension either alone or in combination with other high blood pressure medications. Long treatment with Lozol is required, a therapeutic effect observed after 1-2 weeks of use, maximum is reached in 8-12 weeks and keeps up to 8 weeks.
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Dosage and direction
Take Lozol once a day in mornings before breakfast with or without food. The usual initial dose is 1.25 mg taken as a single daily dose. It may be increased up to 5 mg.
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