Reglan
Common use
Reglan is an anti-vomiting medications which prevents vomit, hiccup, stimulates and coordinates motor activity of gastrointestinal tract. Reglan increases both acetylcholine release from neurons and cholinergic receptor sensitivity to acetylcholine. It is a blocker of serotonin receptors. It increases lower esophageal sphincter tone, stimulates contractions of smooth gastric muscles and at the same time relaxes the pylorus and duodenum. Reglan interacts with the dopamine receptors in the brain and can be effective in treating nausea. This medication is used to treat gastroesophageal reflux disease (GERD), diabetic gastroparesis, atonia and hypotonia of the stomach and intestines, biliary dyskinesia, flatulence, complex therapy of gastric and duodenal ulcers in phase of exacerbation, acceleration of peristaltic activity during gastrointestinal radiocontrast studies.
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Dosage and direction
Usual dose of Reglan for adults is 5-10 mg 3-4 times a day before a meal with a glass of water. In patients with vomiting, severe nausea 10 mg of Reglan is administered intramuscularly (IM) or intravenously. Measure liquid drug with a special dose-measuring spoon. The oral concentrate form of Reglan must be mixed with another liquid (water, fruit juice, soda) or a soft food. Take this medication exactly as prescribed to you, do not use it longer than 3 months.
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