Serophene

Common use
Serophene is an non-steroid anti-estrogen. Mechanism of its action consists in a specific binding with receptor for estrogen in ovary and hypophis. In patients with low estrogen levels in organism it causes estrogen effect and in ones with high estrogen levels it causes anti-estrogen effect. Its small doses increase secretion of gonadotropins (prolactin, Follicle stimulating hormone, FSH and interstitial cell-stimulating hormone), stimulates ovulation; in large doses slows secretion of gonadotropins. In the whole action of Serophene consists in stimulation of ovulation to occur and prepares the body for pregnancy. This medication may be used for male patients with infertility caused by low production of sperm.
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Dosage and direction
Serophene is administered to stimulate ovulation 50 mg 1 time a day at bedtime, starting from 5th day of the menstrual cycle during 5 days (in the absence of the cycle - at any time). In case of no effect (ovulation does not occur within 30 days) increase the dose to 150 mg / day or lengthen the course to 10 days. Take exactly as prescribed, do not take the medication in larger quantities.












































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